Research

Occupational Risk of Arthritis, Including Auto-Immune Rheumatologic Disease

This is a multicenter cross sectional study in collaboration with UCSF which studies the relationship between occupation and the risk of development of rheumatoid arthritis in males 50 years or older.

Chronic Pain Affecting Daily Life study

The division is currently working with Stephanie Judge, MS, a doctoral candidate in Clinical Psychology, and several other UK Healthcare clinics to recruit participants for her dissertation research. The goal of the study is to identify how chronic pain interferes with daily function for individuals with various medical conditions that cause chronic pain and to identify upstream, higher-order behavioral, emotional, and cognitive processes associated with pain interference and functional limitations. Participants complete a one-time survey consisting of several well-established chronic pain assessments and coping measures. Ultimately, identifying specific types of interference and relevant psychosocial processes has the potential to improve how practitioners conceptualize chronic pain and its treatment and lead to more efficient and effective treatments for chronic pain.

STOP-BLOQ study 

STOP-BLOQ study is a national multicenter, NIH-funded study. It aims to test the hypothesis that earlier detection of 2° atrioventricular block in fetuses at highest risk based on maternal SS-A antibody titers or history of a previously affected child, will provide a window of opportunity for successful treatment to reduce the significant morbidity and mortality of this disease in neonates. Women with known positive SSA antibodies and are either pregnant in the first trimester or planning to get pregnant soon might qualify. They will receive frequent fetal echocardiographic assessments as well as teaching to monitor fetal heartbeat at home with a simple Doppler device. Fetuses who show evidence of 2nd degree AV block will get dexamethasone and IVIG based on the study protocol. All neonates will get 12 lead EKG after birth and at 1 year of age regardless of the fetal course. For more information, please email UK study PI, Majd Makhoul, MD at majd.makhoul@uky.edu